Innovation and technology are essential components of medicine and science. There is a constant drive to push our understanding of processes and improve upon existing knowledge further. It is a fairly central tenet of medical culture. Yet, as I've discussed here, it can be difficult to really balance the drive to move forward without trade-offs, sometimes losing the things that work well (though maybe not the most efficient).
This article appeared in The New York Times a couple of weeks ago, and I made a mental note to read it and comment on it. Meier looks at a new technology of hip implants, designed to allow patients to be more active, and the dangers posed by the implants' shedding of metal debris in the patients who received them. It's not just the hip implants, however, there have been an increase of medical technology developments that have posed very significant risks in the pursuit of the latest and greatest. The implants, Meier writes, "show[...] how innovation’s lure led almost everyone to seize on a product promoted as a breakthrough without convincing evidence that it was better or even as good as existing options."
My time as a consultant in oncology biotech/pharma certainly bore this out, as well. The current debates around Avastin for breast cancer struggle with whether incremental benefits (to some) are worth the risks to many. Often new drugs will have a couple of months' improvement over an existing drug, but this potential may be touted as a critical need, even when the trade-offs in quality of life may not be considered by the scientific criteria of risks and benefits.
I would suggest that this is a very American conception of innovation. As one of the physicians interviewed in the article, Dr. Henrik Malchau, notes, "As a non-American, I don’t completely understand it, but there is a phenomenon in the U.S., the latest and the greatest." One of the arguments for the U.S. structure of healthcare and privatization of health (including pharma companies, etc.) has been that the capitalist model generates innovation in a way that government run health simply does not. This position takes American individualism and competition as critical drivers for improvements and innovation in health (and elsewhere). But it's also clear that this model has serious consequences. Even the way in which medical science is funded and regulated reflects this prioritization of privatization as the way to better medicine and knowledge.
What I'm calling for is not a complete abandonment of existing models, but I believe we need to actually take these instances (of which there are many) of failure/serious tradeoffs to be more methodical in how we approach innovation. I realize this is probably highly impractical. People drive technology forward fairly heedless of the individual effects, with the hope that the population-level overall benefit will be worth the costs to the individuals affected. I do believe that one should be circumspect about embracing new products/technologies. And I think that the government could actually make some in-roads into demanding higher standards of proof before approving health-related technologies. Meier writes, at the end of his article, that it is not just a problem with regulation, but also with the attitudes of physicians and patients. This is a cultural problem as much as a structural one.